Earlier publications (1991-2010)
132. Direct Preparation of Heteroaromatic Compounds from Alkenes
Timothy J. Donohoe, Mikhail A. Kabeshov, Akshat H. Rathi and Ian E.D. Smith. Synlett, 2010, 19, 2956–2958.
DOI: 10.1055/s-0030-1259034
131. Identification of Epigenetic DNA Modifications with a Protein Nanopore
Emma V. B. Wallace, David Stoddart, Andrew J. Heron, Ellina Mikhailova, Giovanni Maglia, Timothy J. Donohoe, Hagan Bayley. Chemical Commun., 2010, 46, 8195–8197.
DOI: 10.1039/C0CC02864A
130. A Novel Oxidative Cyclisation onto Vinyl Silanes
Timothy J. Donohoe, Paul C. M. Winship, Ben S. Pilgrim, Daryl S. Walter, Cedric K. A. Callen. Chemical Commun., 2010, 46, 7310–7312.
DOI: 10.1039/c0cc01342k
129. Olefin Cross-Metathesis Based Approaches to Furans: Procedures for the Preparation of Di- and Tri-Substituted Variants
Timothy J. Donohoe, John F. Bower and José A. Basutto. Nature: Protocols, 2010, 5, 2005–2010.
DOI: 10.1038/nprot.2010.147
128. Substituted Pyrroles via Olefin Cross-Metathesis
Timothy J. Donohoe, Nicholas J. Race, John F. Bower and Cedric K. A. Callens. Organic Lett., 2010, 12, 4094–4097.
DOI: 10.1021/ol101681r
127. Synthesis of Cylindricine C and a Formal Synthesis of Cylindricine A
Timothy J. Donohoe, Ptoton M. Brian, Gráinne C. Hargaden and Timothy J.C. O'Riordan. Tetrahedron (Steven Ley Prize Issue), 2010, 66, 6411–6420.
DOI: 10.1016/j.tet.2010.05.044
126. An Expedient Route to Substituted Furans via Olefin Cross Metathesis
Timothy J. Donohoe and John F. Bower. Proc. Natl. Acad. Sci. US, 2010, 107, 3373–3376. This work has been highlighted in PNAS, Science and Nature Chemistry journals with a commentary.
DOI: 10.1073/pnas.0913466107
125. New Modes for the Osmium-Catalyzed Oxidative Cyclization
Timothy. J. Donohoe, Cedric K.A. Callens, Jeremy Parker and Peter J. Lindsay-Scott. Organic Lett., 2010, 12, 1060–1063. This paper was highlighted in the literature, see: Synfacts, 2010, 6, 683.
DOI: 10.1021/ol100046a
124. Regioselective Nucleophilic Addition to Pyridinium Salts: A New Route to Substituted Dihydropyridones
Timothy J. Donohoe, Matthew J. Connolly and Lesley Walton. Organic Lett., 2009, 11, 5562–5565.
DOI: 10.1021/ol902402v
123. Author Profile
Timothy J. Donohoe. Angew. Chem. Int. Ed., 2009, 48, 7119.
DOI: 10.1002/anie.200903879
122. Ring-Closing Metathesis for the Synthesis of Heteroaromatics: Evaluating Routes to Pyridines and Pyridazines
Timothy J. Donohoe, John F. Bower, José A. Basutto, Lisa P. Fishlock, Panayiotis A. Procopiou and Cedric K.A. Callens. Tetrahedron, 2009, 8969–8980.
DOI: 10.1016/j.tet.2009.07.076
121. Concise Syntheses of the Natural Products (+)-Sylvaticin and (+)-cis-Sylvaticin
Timothy J. Donohoe, Robert M. Harris, Oliver Williams, Grainne C. Hargaden, Jeremy Burrows, Jeremy Parker. J. Am. Chem. Soc., 2009, 131, 12854–12861.
DOI: 10.1021/ja9049959
120. Synthesis of (–)-Hygromycin A: Application of Mitsunobu Glycosylation and Tethered Aminohydroxylation
Timothy J. Donohoe, Aida Flores, Carole J. Bataille and Fátima Churruca. Angew. Chem. Int. Ed., 2009, 48, 6507–6510.
DOI: 10.1002/ange.200902840
119. A Lewis Acid Promoted Oxidative Cyclisation
Timothy J. Donohoe, Paul C. M. Winship and Daryl S. Walter. J. Org. Chem., 2009, 74, 6394–6397.
DOI: 10.1021/jo901243y
118. Osmium-Mediated Oxidative Cyclisations: A Study into the Range of Initiators That Facilitate Cyclisation
Timothy J. Donohoe, Katherine M. P. Wheelhouse (née Gosby), Peter J. Lindsay-Scott, Gwydion H. Churchill, Matthew J. Connolly, Sam Butterworth and Paul A. Glossop. Chemistry: An Asian Journal, 2009, 4, 1237–1247.
DOI: 10.1002/asia.200900168
117. Electrochemistry in Tetrahydrofuran and at Low Temperature: Protocol, Procedures and Methods
Ronan Baron, Neil M. Kershaw, Timothy J. Donohoe and Richard G. Compton. Journal of Phys. Org. Chem., 2009, 22, 1136–1141.
DOI: 10.1002/poc.1574
116. The Tethered Aminohydroxylation (TA) Reaction of Amides
Timothy J. Donohoe, Cedric K.A. Callens and Amber L. Thompson. Organic Lett., 2009, 11, 2305–2307.
DOI: 10.1021/ol900631y
115. The Effect of Ortho-Substitution on the Efficacy of Biphenyls in Mediating Electron Transfer from Lithium
Timothy J. Donohoe, Neil M. Kershaw, Ronan Baron and Richard G. Compton. Tetrahedron, 2009, 65, 5377–5384.
DOI: 10.1016/j.tet.2009.04.057
114. Synthesis of Substituted Pyridines and Pyridazines via Ring Closing Metathesis
Timothy J. Donohoe, Lisa P. Fishlock, José A. Basutto, John F. Bower, Panayiotis A. Procopiou and Amber L. Thompson. Chemical Commun., 2009, 21, 3008–3010.
DOI: 10.1039/b904363b
113. Tandem Catalysis in the Polycyclisation of Dienes to Produce Multi-Substituted Tetrahydrofurans
Timothy J. Donohoe, Peter J. Lindsay-Scott and Jeremy S. Parker. Tetrahedron Letters, 2009, 50, 3523–3526.
DOI: 10.1016/j.tetlet.2009.03.027
112. Ruthenium Catalysed Isomerization of Terminal Olefins: Applications to Synthesis
Timothy J. Donohoe, Timothy J.C. O'Riordan and Carla P. Rosa. Angew. Chem. Int. Ed., 2009, 48, 1014–1017.
DOI: 10.1002/anie.200804617
111. Quantitative Voltammetry of the Reduction of Methyl Benzoate in THF Reveals Strong Ion Pairing of the Radical Anion with Tetra-n-Butyl Cations
Ronan Baron, Neil M. Kershaw, Timothy J. Donohoe and Richard G. Compton. Journal of Phys. Org. Chem., 2009, 22, 247–253.
DOI: 10.1002/poc.1462
110. Synthesis of (+)-DGDP and (–)-7-Epialexine
Timothy J. Donohoe, Matthew D. Cheeseman, Timothy J.C. O'Riordan and Jessica A. Kershaw. Org. Biomol. Chem., 2008, 6, 3896–3898.
DOI: 10.1039/b815332a
109. Alkali Metal Reductions of Organic Molecules: Why Mediated Electron Transfer from Lithium Is Faster Than Direct Reduction
Neil Rees, Ronan Baron, Neil Kershaw, Timothy J. Donohoe, Richard J. Compton. J. Am. Chem. Soc., 2008, 130, 12256–12257.
DOI: 10.1021/ja805086w
108. Flexible Strategy for the Synthesis of Pyrrolizidine Alkaloids
Timothy J. Donohoe, Rhian Thomas, Matthew Cheeseman, Caroline Rigby, Ian Linney and Gurdip Bhalay. Organic Lett., 2008, 10, 3615–3618.
DOI: 10.1021/ol801415d
107. Synthesis of (–)-(Z)-Deoxypukalide
Timothy J. Donohoe, Alan Ironmonger and Neil M. Kershaw. Angew. Chem. Int. Ed., 2008, 47, 7314–7316.
DOI: 10.1002/anie.200802703
106. Ring-Closing Metathesis as a Key Step in the Synthesis of 2-Pyridones and Pyridine Triflates
Timothy J. Donohoe, Lisa P. Fishlock and Panayiotis A. Procopiou. Synthesis, 2008, 129, 2665–2667. Practical Synthetic Procedure.
DOI: 10.1055/s-2008-1067180
105. Ring-Closing Metathesis: Novel Routes to Aromatic Heterocycles
Timothy J. Donohoe, Lisa P. Fishlock and Pan A. Procopiou. Chemistry: A European Journal, 2008, 14, 5716–5726.
DOI: 10.1002/chem.200800130
104. Pyridine-N-Oxide as a Mild Reoxidant Which Transforms Osmium Catalysed Oxidative Cyclisation
Timothy J. Donohoe, Katherine M.P. Wheelhouse (née) Gosby, Peter J. Lindsay-Scott, Paul A. Glossop, Ian A. Nash and Jeremy S. Parker. Angew. Chem. Int. Ed., 2008, 47, 2872–2875.
DOI: 10.1002/anie.200705425
103. Hydride Shift Generated Oxonium Ions: Evidence for Mechanism and Intramolecular Trapping Experiments to Form trans THF Derivatives
Timothy J. Donohoe, Oliver Williams and Gwydion H. Churchill. Angew. Chem. Int. Ed., 2008, 47, 2869–2871.
DOI: 10.1002/anie.200705340
102. A Metathesis-Based Approach to the Synthesis of 2-Pyridones and Pyridines
Timothy J. Donohoe, Lisa P. Fishlock and Pan A. Procopiou. Organic Lett., 2008, 10, 285–288.
DOI: 10.1021/ol702684d
101. Flexible Metathesis-Based Approaches to Highly Functionalised Furans and Pyrroles
Timothy J. Donohoe, Neil M. Kershaw, Allan J. Orr, Katherine M. P. Wheelhouse (née Gosby), Lisa P. Fishlock, Adam R. Lacy, Matilda Bingham and Panayiotis A. Procopiou. Tetrahedron, 2008, 64, 809–820.
DOI: 10.1016/j.tet.2007.10.059
100. Electrosynthetic Reduction of 1-Iodoadamantane Forming 1,1′-Biadamantane and Adamantane in Aprotic Solvents: Insonation Switches the Mechanism from Dimerisation to Exclusive Monomer Formation
Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton. Ultrasonics Sonochemistry, 2007, 14, 502–508.
DOI: 10.1016/j.ultsonch.2006.11.007
99. Cryoelectrochemical Reduction of a Phenyl Sulfide in Tetrahydrofuran: Mediated Reduction Gives Different Products Compared to Direct Reduction
Alexander V. Burasov, Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton. J. Phys. Org. Chem., 2007, 20, 144–150.
DOI: 10.1002/poc.1138
98. Electrocatalytic Reduction of Alkyl Iodides in Tetrahydrofuran at Silver Electrodes
Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton. J. Phys. Org. Chem., 2007, 20, 115–121.
DOI: 10.1002/poc.1133
97. Kinetics and Thermodynamics of the Li/Li+ Couple in Tetrahydrofuran at Low Temperatures (195–295 K)
Christoper A. Paddon, Sarah E. Ward Jones, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton. J. Phys. Org. Chem., 2007, 20, 677–684.
DOI: 10.1002/poc.1230
96. A Concise and Efficient Synthesis of (−)-Allosamizoline
Timothy J. Donohoe and Carla P. Rosa. Organic Lett., 2007, 9, 5509–5511.
DOI: 10.1021/ol702449m
95. Mediated Electron Transfer from Lithium Investigated Voltammetrically in Tetrahydrofuran: Why Are Some Mediators More Effective Reducing Reagents Than Others?
Natasha C.L. Wood, Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton. J. Phys. Org. Chem., 2007, 20, 732–742.
DOI: 10.1002/poc.1232
94. The Partial Reduction of Electron-Deficient Pyrroles: Procedures Describing Both Birch (Li/NH3) and Ammonia-Free (Li/DBB) Conditions
Timothy J. Donohoe, Rhian E. Thomas. Nature: Protocols, 2007, 2, 1888–1895. Cover picture for this issue.
DOI: 10.1038/nprot.2007.245
93. The Tethered Aminohydroxylation: Dramatic Improvements to the Process
Timothy J. Donohoe, Carole J. R. Bataille, William Gattrell, Johannes Kloesges and Emilie Rossignol. Organic Lett., 2007, 9, 1725–1728.
DOI: 10.1021/ol070430v
92. A Metathesis Based Approach to the Synthesis of Furans
Timothy J. Donohoe, Lisa P. Fishlock, Adam R. Lacy, and Panayiotis A. Procopiou. Organic Lett., 2007, 9, 953–956.
DOI: 10.1021/ol062933r
91. Coulometry on the Voltammetric Timescale: Microdisk Potential-Step Chronoamperometry in Aprotic Solvents Reliably Measures the Number of Electrons Transferred in an Electrode Process Simultaneously with the Diffusion Coefficients of the Electro...
Christopher A. Paddon, Debbie S. Silvester, Farrah L. Bhatti, Timothy J. Donohoe, Richard G. Compton. Electroanalysis, 2007, 19, 11–22.
DOI: 10.1002/elan.200603667
90. Partial Reduction of Pyrroles: Application to Natural Product Synthesis
Timothy J. Donohoe, and Rhian E. Thomas. The Chemical Record, 2007, 7, 180–190.
DOI: 10.1002/tcr.20115
89. Synthesis of the Pyrrolidinone Core of KSM-2690 B
Timothy J. Donohoe, Jessica Chiu, Rhian E Thomas. Organic Lett., 2007, 9, 421–424.
DOI: 10.1021/ol062705x
88. Total Synthesis of (+)-cis-Sylvaticin: Double Oxidative Cyclisation Reactions Catalyzed by Osmium
Timothy J. Donohoe, Robert M. Harris, Jeremy Burrows and Jeremy Parker. J. Am. Chem. Soc., 2006, 128, 13704–13705.
DOI: 10.1021/ja0660148
87. Stereoselective Synthesis of Pyrrolidines: Catalytic Oxidative Cyclisations Mediated by Osmium
Timothy J. Donohoe, Gwydion H. Churchill, Katherine M. P. Wheelhouse (née Gosby) and Paul A. Glossop. Angew. Chem. Int. Ed., 2006, 45, 8025–8028.
DOI: 10.1002/anie.200603240
86. Cryo-Electrochemistry in Tetrahydrofuran: The Regioselective Electrochemical Reduction of a Phenyl Sulfone: Fast-Scan Cyclic Voltammetry Investigations
Nicole Fietkaua, Christopher A. Paddon, Farrah L. Bhattib, Timothy J. Donohoe and Richard G. Compton. Journal of Electroanalytical Chemistry, 2006, 593, 131–141.
DOI: 10.1016/j.jelechem.2006.03.004
85. Cryovoltammetrically Probing Functional Group Reductive Cleavage: Alkyl-Sulfur versus Aryl-Sulfur Bond Cleavage in an Alkyl Naphthyl Thioether under Single Electron Transfer Is Temperature Switchable
Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton. Chem. Commun., 2006, 3402–2404.
DOI: 10.1039/B606638K
84. Highlights of Natural Product Synthesis
Timothy J. Donohoe, Carole J. R. Bataille and Gwydion H. Churchill. Annual Rep. Prog. Chem. Sect. B, 2006, 102, 98–122.
DOI: 10.1039/B515095G
83. An Enzymatic Approach to the Desymmetrisation of Disubstituted Pyrrolines
Timothy J. Donohoe, Caroline L. Rigby, Rhian E. Thomas, William F. Nieuwenhuys, Farrah L. Bhatti, Andrew R. Cowley, Gurdip Bhalay and Ian D. Linney. J. Org. Chem., 2006, 71, 6298–6301.
DOI: 10.1021/jo060926a
82. Cryo-Electrochemistry in Tetrahydrofuran: The Electrochemical Reduction of a Phenyl Thioether: [(3-{[trans-4-(Methoxymethoxy)cyclohexyl]oxy}propyl)thio]benzene
Christopher A. Paddon, Farrah L. Bhatti, Timothy J. Donohoe and Richard G. Compton. Journal of Electroanalytical Chemistry, 2006, 589, 187–194.
DOI: 10.1016/j.jelechem.2006.02.010
81. New Osmium-Based Reagent for the Dihydroxylation of Alkenes
Timothy J. Donohoe, Robert M. Harris, Sam Butterworth, Jeremy N. Burrows, Andrew Cowley, and Jeremy S. Parker. J. Org. Chem., 2006, 71, 4481–4489.
DOI: 10.1021/jo060301c
80. N-Sulfonyloxy Carbamates as Re-Oxidants for the Tethered Aminohydroxylation Reaction
Timothy J. Donohoe, Majid J. Chughtai, David J. Klauber, David Griffin and Andrew D. Campbell. J. Am. Chem. Soc., 2006, 128, 2514–2515.
DOI: 10.1021/ja057389g
79. The Ammonia-Free Partial Reduction of Substituted Pyridinium Salts
Timothy J. Donohoe, Dale J. Johnson, Laura H. Mace, Rhian E. Thomas, Jessica Y. K. Chiu, Jason S. Rodrigues, Richard G. Compton, Craig E. Banks, Peter Tomcik, Mark J. Bamford and Osamu Ichihara. Org. Biomol. Chem., 2006, 4, 1071–1084.
DOI: 10.1039/B517462G
78. Ring Closing Metathesis as a Basis for the Construction of Aromatic Compounds
Timothy J. Donohoe, Allan J. Orr and Matilda Bingham. Angew. Chem. Int Ed., 2006, 45, 2664–2670.
DOI: 10.1002/anie.200503512
77. A Non-Carbohydrate Based Approach to Polyhydroxylated Pyrrolidizines; Total Syntheses of the Natural Products Hyacinthacine A1 and 1-Epiaustraline
Timothy J. Donohoe, Herman O. Sintim and Jackie Hollinshead. J. Org. Chem., 2005, 70, 7297–7304.
DOI: 10.1021/jo050977s
76. Oxidative Cyclisations of Diols Derived from 1,5-Dienes: Formation of Enantiopure cis-Tetrahydrofurans Using Catalytic Osmium Tetroxide and a Formal Synthesis of (+)-cis-Solamin
Timothy J. Donohoe and Sam Butterworth. Angew. Chem. Int. Ed., 2005, 44, 4766–4768.
DOI: 10.1002/anie.200500513
75. A Metathesis Approach to Aromatic Heterocycles
Timothy J. Donohoe, Allan J. Orr, Katherine Gosby and Matilda Bingham. Eur. J. Org. Chem., 2005, 10, 1969–1971.
DOI: 10.1002/ejoc.200500113
74. A Concise and Enantioselective Synthesis of the Aminocyclitol Core of Hygromycin A
Timothy J. Donohoe, Peter D. Johnson, Richard J. Pye and Martine Keenan. Organic Lett., 2005, 7, 1275–1277.
DOI: 10.1021/ol0473750
73. Utility of the Ammonia-Free Birch Reduction of Electron-Deficient Pyrroles: Total Synthesis of the 20S Proteasome Inhibitor, Clasto-Lactacystin Beta-Lactone
Timothy J. Donohoe, Herman O. Sintim, Leena Sisangia, Karl W. Ace, Paul M. Guyo, Andrew Cowley and John D. Harling. Chemistry: A European Journal, 2005, 11, 4227–4238.
DOI: 10.1002/chem.200401119
72. Partial Reduction of Pyridinium Salts as a Versatile Route to Dihydropyridones
Timothy J. Donohoe, D. Johnson, L. H. Mace, O. Ichihara and M. Bamford. Organic Lett., 2005, 7, 453–437.
DOI: 10.1021/ol0476624
71. Cryoelectrochemistry: Electrochemical Reduction of 2(RS)-Methyl 1-(tert-Butoxycarbonyl)-2-Iodomethyl-2,5-Dihydropyrrole-2-Carboxylate
Craig E. Banks, Russell G. Evans, Jason Rodrigues, Peter G. Turner, Timothy J. Donohoe and Richard G. Compton. Tetrahedron, 2005, 61, 2365–2372.
DOI: 10.1016/j.tet.2005.01.022
70. Enantioselective Partial Reduction of 2,5-Disubstituted Pyrroles via a Chiral Protonation Approach
Timothy J. Donohoe, Catherine E. Headley, Caroline L. Rigby, Graeme C. Freestone, Rick P. C. Cousins and Gurdip Bhlay. Organic Lett. 2004, 6, 3055–3058.
DOI: 10.1021/ol049014q
69. Efficient Acyclic Stereocontrol Using the Tethered Aminohydroxylation Reaction
Timothy J. Donohoe, Peter D. Johnson, Martine Keenan and Richard J. Pye. Organic Lett. 2004, 6, 2583–2585.
DOI: 10.1021/ol049136i
68. An Efficient Synthesis of (±)-1 Epiaustraline
Timothy J. Donohoe and Herman O. Sintim. Organic Lett. 2004, 6, 2003–2006.
DOI: 10.1021/ol049397s
67. Rearrangement of Pyrrolines Derived from the Birch Reduction of Electron-Deficient Pyrroles: Radical Ring-Expansion to Substituted Tetrahydropyridines
Timothy J. Donohoe, Rick P. C. Cousins and Peter Turner. Chem. Commun. 2004, 1422–1423.
DOI: 10.1039/B404002C
66. Low Temperature Electrochemistry as a Mechanistic Probe for the Partial Reduction of Heterocycles
Timothy J. Donohoe, Richard Compton, Dale Johnson and Jay D. Wadhawan. Tetrahedron, 2004, 60, 5945–5952.
DOI: 10.1016/j.tet.2004.05.027
65. An Efficient Synthesis of Lactacysin ß-Lactone
Timothy J. Donohoe, Leena Sisangia, Herman O. Sintim and John D. Harling. Angew. Chem. Int. Ed. 2004, 43, 2293–2296.
DOI: 10.1002/anie.200453843
64. Enantiopure Oxazolidinones as Chiral Acids in the Asymmetric Protonation of N-Boc Pyrrole Derived Enolates
Timothy J. Donohoe and David Carbery. Chem. Commun. 2004, 722–723.
DOI: 10.1039/B316719D
63. Synthesis of (±)-Secosyrin 1 and a Formal Synthesis of (–)-Secosyrin 1
Timothy J. Donohoe, John W. Fisher and Paul J. Edwards. Organic Lett. 2004, 6, 465–467.
DOI: 10.1021/ol0362313
62. Trichloro-oxazolines as Activated Donors for Aminosugar Coupling
Timothy J. Donohoe, James G. Logan and David D. P. Laffan. Organic Lett. 2003, 5, 4995–4998.
DOI: 10.1021/ol0359620
61. Calcium Mobilisation and CCK Secretion Induced by Modified Fatty Acids and Latex Microspheres Reveal Dual Receptor Mechanisms for Lipid Stimulation of STC-1 Cells
S. Kazmi, R. S. P. Benson, T. J. Donohoe, M. N. Jones, M. Wickham, D. G. Thompson, R. M. Case. Journal of Physiology, 2003, 553, 759–773.
DOI: 10.1113/jphysiol.2003.051680
60. Osmium Tetroxide
Timothy J. Donohoe, Robert Harris and Majid Chugtai. Encyclopedia of Reagents for Organic Synthesis, 2003.
DOI: 10.1002/047084289X.ro007.pub2
59. Scope of the Reductive Aldol Reaction: Application to Aromatic Carbocycles and Heterocycles
Timothy J. Donohoe, David House and K. W. Ace. Org. Biomol. Chem. 2003, 1, 2025–2028.
DOI: 10.1039/b305189g
58. The Tethered Aminohydroxylation (TA) Reaction
Timothy J. Donohoe, Peter D. Johnson and Richard J. Pye. Org. Biomol. Chem. 2003, 1, 2025–2028.
DOI: 10.1039/b305189g
57. Scope of the Directed Dihydroxylation: Application to Cyclic Homoallylic Alcohols and Trihaloacetamides
Timothy J. Donohoe, Lee Mitchell, Michael J. Waring, Madeleine Helliwell, Andrew Bell, and Nicholas J. Newcombe. Org. Biomol. Chem. 2003, 1, 2173–2186.
DOI: 10.1039/b303081d
56. Flexibility in the Partial Reduction of 2,5-Disubstituted Pyrroles: Application to the Synthesis of DMDP
Timothy J. Donohoe, Catherine E. Headley, Rick P. C. Cousins and Andrew Cowley. Organic Lett. 2003, 5, 999–1002.
DOI: 10.1021/ol027504h
55. A General Oxidative Cyclisation of 1,5-Dienes Using Catalytic Osmium Tetroxide
Timothy J. Donohoe and Sam Butterworth. Angew. Chem. Int. Ed. 2003, 42, 948–951.
DOI: 10.1002/anie.200390253
54. Diastereoselective Reductive Aldol Reactions of BOC-Protected Electron Deficient Pyrroles
Timothy J. Donohoe and David House. Tetrahedron Letters, 2003, 44, 1095–1098.
DOI: 10.1016/S0040-4039(02)02672-2
53. The Directed Dihydroxylation of Cyclic Allylic Alcohols and Trichloroacetamides Using OsO4/TMEDA
Timothy J. Donohoe, Kevin Blades, Peter R. Moore, Michael J. Waring, Jon J. G. Winter, Madeleine Helliwell, Nicholas J. Newcombe and Geoffrey Stemp. J. Org. Chem. 2002, 67, 7946–7956.
DOI: 10.1021/jo026161y
52. The Tethered Aminohydroxylation (TA) of Cyclic Allylic Carbamates
Timothy J. Donohoe, Peter D. Johnson, Andrew Cowley and Martine Keenan. J. Am. Chem. Soc. 2002, 124, 12934–12935.
DOI: 10.1021/ja0276117
51. Synthesis of Enantiopure Dihydropyranones: Aldol-Based Ring Expansion of Dihydrofurans
Timothy J. Donohoe, Ali Raoof, Graeme C. Freestone, Ian D. Linney, Andrew Cowley and Madeleine Helliwell. Organic Lett. 2002, 4, 3059–3062.
DOI: 10.1021/ol0263595
50. Partial Reduction of 3-Heteroatom Substituted 2-Furoic Acids: The Role of an Ortho Group on Viability and Stereoselectivity
Timothy J. Donohoe, Andrew A. Calabrese, Jean-Baptiste Guillermin, Christopher. S. Frampton and Daryl Walter. J. Chem. Soc. Perkin Transactions 1, 2002, 1748–1756.
DOI: 10.1039/B203437A
49. Ammonia Free Reduction of Aromatic Compounds Using Lithium Di-tert-butylbiphenyl (LiDBB)
Timothy J. Donohoe and David House. J. Org. Chem. 2002, 67, 5015–5018.
DOI: 10.1021/jo0257593
48. Preparation of (+)-Nemorensic Acid and Approaches to Nemorensine Using the Partial Reduction of Electron Deficient Furans
Timothy J. Donohoe, Jean-Baptiste Guillermin and Daryl S. Walter. J. Chem. Soc. Perkin Transactions 1, 2002, 1369–1375.
DOI: 10.1039/B202514K
47. Development of the Directed Dihydroxylation Reaction
Timothy J. Donohoe. Synlett, 2002, 8, 1223–1232.
DOI: 10.1055/s-2002-32947
46. Transformations of 3,4-Disubstituted Pyridines under Dissolving Metal Conditions—Partial Reduction Followed by Radical Cyclisation
Timothy J Donohoe, Laura Mace, Madeleine Helliwell and Osamu Ichihara. Synlett, 2002, 2, 331–333.
DOI: 10.1055/s-2002-19757
45. Homoallylic Alcohols and Trichloroacetamides as Hydrogen Bond Donors for Directed Dihydroxylation
Timothy J. Donohoe, L. Mitchell, M. J. Waring, M. Helliwell, A. Bell and N. J. Newcombe. Tetrahedron Letters, 2001, 42, 8951–8954.
DOI: 10.1016/S0040-4039(01)01999-2
44. The Regioselective Aminohydroxylation of Allylic Carbamates
Timothy J. Donohoe, Peter D. Johnson, Madeleine Helliwell, and Martine Keenan. Chem. Commun. 2001, 2078.
DOI: 10.1039/B107253F
43. Silyl Substituted Furans in the Stereoselective Birch Reduction
Timothy J Donohoe, Andrew A. Calabrese, Jean-Baptiste Guillermin and Daryl S. Walter. Tetrahedron Letters, 2001, 42, 5841.
DOI: 10.1016/S0040-4039(01)01151-0
42. Use of Dissolving Metals in the Partial Reduction of Pyridines: Formation of 2-Alkyl-1,2-Dihydropyridines
T. J. Donohoe, Andrew J. McRiner, Madeleine Helliwell and Peter Sheldrake. J. Chem. Soc. Perkin Transactions 1, 2001, 1435–1445.
DOI: 10.1039/B101662H
41. Partial Reduction of Annulated Heterocycles as a General Route to Medium Rings Containing Oxygen and Nitrogen
Timothy J. Donohoe, Ali Raoof, Ian D. Linney and Madeleine Helliwell. Organic Lett. 2001, 3, 861–864.
DOI: 10.1021/ol007035o
40. Hydrogen Bonding Control in the Oxidative Cyclisation of 1,5-Dienes
Timothy J. Donohoe, Jonathan J. G. Winter, M. Helliwell and Geoffrey Stemp. Tetrahedron Letters, 2001, 42, 971–974.
DOI: 10.1016/S0040-4039(00)02225-5
39. Partial Reduction of Electron-Deficient Pyridines
T. J. Donohoe, A. J. McRiner and P. Sheldrake. Organic Lett. 2000, 2, 3861–3863.
DOI: 10.1021/ol0065930
38. Stereoselective Reduction of Chiral 2-Furoic Acid Derivatives Using Group I Metals in Ammonia
Timothy J. Donohoe, Andrew A. Calabrese, Clare A. Stevenson and Tamara Ladduwahetty. J. Chem. Soc. Perkin Transactions 1, 2000, 3724.
DOI: 10.1039/B006390H
37. Oxidation and Reduction in Organic Synthesis: OUP Chemistry Primer No. 6
Timothy J. Donohoe. Oxford University Press, 2000, ISBN 0198556640
36. A Syn Selective Dihydroxylation of Cyclic Allylic Trichloroacetamides Using Catalytic Osmium Tetroxide
Kevin Blades, Timothy J. Donohoe, Jonathan J. G. Winter and Geoffrey Stemp. Tetrahedron Letters, 2000, 41, 4701–4704.
DOI: 10.1016/S0040-4039(00)00714-0
35. The Synthesis of (+)-Nemorensic Acid
Timothy J. Donohoe, J-B. Guillermin, C. Frampton and D. S. Walters. J. Chem Soc., Chem. Commun. 2000, 465–466.
DOI: 10.1039/B000565G
34. The Partial Reduction of Heterocycles: An Alternative to the Birch Reduction
Timothy J. Donohoe, Rakesh R. Harji and Rick P. C. Cousins. Tetrahedron Letters, 2000, 41, 1331–1334.
DOI: 10.1016/S0040-4039(99)02315-1
33. Stereoselective Reductive Alkylation of 2,5-Disubstituted Pyrroles: A Role for Naphthalene in the Partial Reduction of Heterocycles
Timothy J. Donohoe, Rakesh R. Harji and Rick P. C. Cousins. Tetrahedron Letters, 2000, 41, 1327–1330.
DOI: 10.1016/S0040-4039(99)02314-X
32. Reductive Aldol Reactions on Aromatic Heterocycles
Timothy J. Donohoe, Karl W. Ace, Paul M. Guyo, Madeleine Helliwell and Jeffrey McKenna. Tetrahedron Letters, 2000, 41, 989–993.
DOI: 10.1016/S0040-4039(99)02224-8
31. Enhanced Stereoselectivity in the Catalytic Dihydroxylation of Acyclic Allylic Alcohols
Timothy J. Donohoe, Michael J. Waring, and Nicholas J. Newcombe. Synlett, 2000, 149–151.
DOI: 10.1055/s-2000-6457
30. 1H- and 2H-Isoindoles
Timothy J. Donohoe. Science of Synthesis, Georg Thieme Verlag, 2000, 10, 653–692. (Review)
29. Birch Reduction of Aromatic Heterocycles
Timothy J. Donohoe, P. M. Guyo and A. Raoof. Targets in Heterocyclic Systems, Italian Society of Chemistry, 1999, 3, 117–145 (Review).
28. Syn Stereocontrol in the Directed Dihydroxylation of Ayclic Allylic Alcohols
Timothy J. Donohoe, Michael J. Waring and Nicholas J. Newcombe. Tetrahedron Letters, 1999, 40, 6881–6884.
DOI: 10.1016/S0040-4039(99)01371-4
27. The Synthesis of (–)-cis and (–)-trans-Crobarbatic Acid
Timothy J. Donohoe, C. A. Stevenson M. Helliwell, R. Irshad and T. Ladduwahetty. Tetrahedron: Asymmetry, 1999, 10, 1315–1320.
DOI: 10.1016/S0957-4166(99)00097-X
26. Directed Dihydroxylation of Allylic Trichloroacetamides
Timothy J. Donohoe, Kevin Blades, Peter R. Moore, Jonathan J. G. Winter, Madeleine Helliwell and Geoffrey Stemp. J. Org. Chem. 1999, 64, 2980–2981.
DOI: 10.1021/jo982468e
25. Stereoselectivity in the Double Reductive Alkylation of Pyrroles: Synthesis of cis-3,4-Disubstituted Pyrrolidines
Timothy J. Donohoe, Rakesh R. Harji and Rick P. C. Cousins. J. Chem Soc., Chem. Commun. 1999, 141–142.
DOI: 10.1039/A809193E
24. The Stereoselective Birch Reduction of Pyrroles
Timothy J. Donohoe, P. M. Guyo and M. Helliwell. Tetrahedron Letters, 1999, 40, 435–438.
DOI: 10.1016/S0040-4039(98)02395-8
23. Synthesis of Amino-Sugars Using the Directed Dihydroxylation Reaction
Timothy J. Donohoe, Kevin Blades and Madeleine Helliwell. J. Chem Soc., Chem. Commun. 1999, 1733–1734.
DOI: 10.1039/A904991F
22. The Synthesis of (+)-Pericosine B
Timothy J. Donohoe, K. Blades, M. Helliwell, M. J. Waring, and N. J. Newcombe. Tetrahedron Lett. 1998, 39, 8755–8758.
DOI: 10.1016/S0040-4039(98)01989-3
21. The Birch Reduction of 3-Substituted Pyrroles
Timothy J. Donohoe, P. M. Guyo, R. R. Harji and R. P. C. Cousins. Tetrahedron Lett. 1998, 39, 3075–3078.
DOI: 10.1016/S0040-4039(98)00362-1
20. Stereoselectivity in the Birch Reduction of 2-Furoic Acid Derivatives
Timothy J. Donohoe, M. Helliwell, C. A. Stevenson and T. Ladduwahetty. Tetrahedron Lett., 1998, 39, 3071–3074.
DOI: 10.1016/S0040-4039(98)00361-X
19. Applications of Stoichiometric Organotransition Metal Complexes in Organic Synthesis
Timothy J. Donohoe, Rakesh R. Harji, Peter R. Moore and Michael J. Waring. J. Chem. Soc. Perkin Transactions 1, 1998, 819–859. (Review)
DOI: 10.1039/A706382B
18. The Reduction of Electron-Deficient Pyrroles Using Group I and II Metals in Ammonia
Timothy J. Donohoe, P. M. Guyo, R. L. Beddoes and M. Helliwell. J. Chem. Soc. Perkin Transactions 1, 1998, 667–672.
DOI: 10.1039/A707661D
17. The Directed Dihydroxylation of Allylic Alcohols
Timothy J. Donohoe, Peter R. Moore, Michael J. Waring and Nicholas J. Newcombe. Tetrahedron Lett. 1997, 38, 5027–5030.
DOI: 10.1016/S0040-4039(97)01061-7
16. Applications of Stoichiometric Organotransition Metal Complexes in Organic Synthesis
Timothy J. Donohoe, Paul M. Guyo, Peter R. Moore and Clare A. Stevenson. Cont. Org. Syn. 1997, 4, 22–39. (Review)
DOI: 10.1039/CO9970400022
15. Studies on the Role of Conformation and of Hydrogen-Bonding on the Dihydroxylation of Cyclic Allylic Alcohols: Application to the Synthesis of Conduritol D
Timothy J. Donohoe, Peter R. Moore and Roy L. Beddoes. J. Chem. Soc. Perkin Transactions 1, 1997, 43–51.
DOI: 10.1039/A604052G
14. Birch Reduction of Electron-Deficient Pyrroles
Timothy J. Donohoe and Paul M. Guyo. J. Org. Chem. 1996, 61, 7664–7665.
DOI: 10.1021/jo961688u
13. On the Dihydroxylation of Cyclic Allylic Alcohols
Timothy J. Donohoe, Rina Garg and Peter R. Moore. Tetrahedron Lett. 1996, 37, 3407–3410.
DOI: 10.1016/0040-4039(96)00558-8
12. Prospects for Stereocontrol in the Reduction of Aromatic Compounds
Timothy J. Donohoe, Rina Garg and Clare A. Stevenson. Tetrahedron: Asymmetry, 1996, 7, 317–344. (Review)
DOI: 10.1016/0957-4166(96)00001-8
11. Stoichiometric Organotransition Metals in Organic Synthesis
Timothy J. Donohoe. Cont. Org. Syn. 1996, 3, 1–18. (Review)
DOI: 10.1039/CO9960300001
10. Taxane Diterpenes 3: Formation of the Eight-Membered B-Ring by Semi-Pinacol Rearrangement
Philip Magnus, Louis Diorazio, Timothy J. Donohoe, Melvyn Giles, Philip Pye, James Tarrant and Stephen Thom. Tetrahedron, 1996, 52, 14147–14176.
DOI: 10.1016/0040-4020(96)00865-4
9. Taxane Diterpenes 2: Synthesis of the 7-Deoxy ABC Taxane Skeleton, and Reactions of the A-Ring
Philip Magnus, John Booth, Louis Diorazio, Timothy J. Donohoe, Vince Lynch, Nicholas Magnus, José Mendoza, Philip Pye and James G. Tarrant. Tetrahedron, 1996, 52, 14103–14146.
DOI: 10.1016/0040-4020(96)00866-6
8. Taxane Diterpenes 1: Control of Relative and Absolute Stereochemistry in Intramolecular Pyrylium Ylide-Alkene Cyclizations for the Synthesis of Taxol Precursors
William E. Bauta, John Booth, Mary E. Bos, Mark DeLuca, Louis Diorazio, Timothy J. Donohoe, Christopher Frost, Nicholas Magnus, Philip Magnus, José Mendoza, Philip Pye, James G. Tarrant, Stephen Thom and Feroze Ujjainwalla. Tetrahedron, 1996, 52, 14081–14102.
DOI: 10.1016/0040-4020(96)00867-8
7. New Strategy for the Synthesis of the Taxane Diterpenes: Formation of the Eight-Membered B-Ring of Taxol by Semi-Pinacol Rearrangement
P. Magnus, L. Diorazio, T. J. Donohoe, M. Giles, P. Pye, J. Tarrant and S. Thom. J. Chem. Soc., Chem. Commun. 1995, 1935–1936.
DOI: 10.1039/C39950001935
6. New Strategy for the Synthesis of the Taxane Diterpenes: Formation of the BC-Rings of Taxol via a [5+2]-Pyrylium Ylide-Alkene Cyclization, Ring Expansion Strategy
W. Bauta, J. Booth, M. Bos, M. DeLuca, L. Diorazio, T. J. Donohoe, N. Magnus, P. Magnus, J. Mendoza, P. Pye, J. Tarrant, S. Thom and F. Ujjainwalla. Tetrahedron Lett. 1995, 36, 5327–5330.
DOI: 10.1016/0040-4039(95)01083-T
5. Arene Chromium Tricarbonyl Stabilised Benzylic Carbocations
Stephen G. Davies and Timothy J. Donohoe. Synlett, 1993, 323–332.
DOI: 10.1055/s-1993-22443
4. Asymmetric Synthesis via Homochiral o-Anisaldehyde Chromium Tricarbonyl
Stephen G. Davies and Timothy J. Donohoe, H. Werner, A. G. Griesbeck, W. Adam, G. Bringmann, and W. Kiefer (Eds). Vieweg, Braunschweig, Selective Reactions of Metal-Activated Molecules, Vieweg, Braunschweig, 1992, 9–17. (Review)
DOI: 10.1016/S0957-4166(00)82002-9
3. Stereoselective Manipulation of Acetals Derived from o-Substituted Benzaldehyde Chromium Tricarbonyl Complexes
Stephen G. Davies, Timothy J. Donohoe and J. M. J. Williams. Pure and Appl. Chem. 1992, 64, 379–386. (Review)
DOI: 10.1351/pac199264030379
2. Asymmetric Synthesis of 2-Aryl-Tetrahydropyrans via Arene Chromium Tricarbonyl Methodology 2: 2-Aryl-3-Ethyl-4-Chloro-Tetrahydropyran
Stephen. G. Davies, Timothy J. Donohoe and M. Anne Lister. Tetrahedron: Asymmetry, 1991, 2, 1089–1092.
DOI: 10.1016/S0957-4166(00)82003-0
1. Asymmetric Synthesis of 2-Aryl-Tetrahydropyrans via Arene Chromium Tricarbonyl Methodology 1: cis-2-Aryl-4-Chloro-Tetrahydropyrans
Stephen G. Davies, Timothy J. Donohoe and M. Anne Lister. Tetrahedron: Asymmetry, 1991, 2, 1085–1088.
DOI: 10.1016/S0957-4166(00)82002-9