2011-2014

168. Short and Efficient Syntheses of Protoberberine Alkaloids Using Palladium Catalyzed Enolate Arylation
Alice E. Gatland, Ben S. Pilgrim, Panayiotis A. Procopiou and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2014, 53, 14555–14558.
DOI: 10.1002/anie.201409164
 



167. Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein:Small Molecule Interaction
Michael Fairhead, Di Shen, Louis K. M. Chan, Ed D. Lowe, Timothy J. Donohoe, Mark Howarth. Bioorganic & Medicinal Chemistry, 2014, 22, 5476–5486.
DOI: 10.1016/j.bmc.2014.07.029
 



 166. New Methods for the Synthesis of Naphthyl Amines; Application to the Synthesis of Dihydrosanguinarine, Sanguinarine, Oxysanguinarine and (±)-Maclekarpines B and C
Matthew R. Tatton, Iain Simpson and Timothy J. Donohoe. Chem. Commun., 2014, 50, 11314–11316.
DOI: 10.1039/C4CC05209A
 


 

165. De Novo Synthesis of Multi-Substituted Aryl Amines Using Alkene Cross Metathesis
Matthew Tatton, Iain Simpson and Timothy J. Donohoe. Organic Letters, 2014, 16, 1920–1923.
DOI: 10.1021/ol500441q
 



164. Rhodium-Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of Alpha-Branched Products
Louis K. M. Chan, Darren L. Poole, Di Shen, Mark P. Healy and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2014, 53, 761–765. Designated as a HOT paper, featured as the back cover.
DOI: 10.1002/anie.201307950
 


 

163. Total Synthesis of the Antitumor Antibiotic (±)-Streptonigrin: First and Second Generation Routes for De Novo Pyridine Formation Using Ring Closing Metathesis
Timothy Donohoe, Christopher Jones, Anne Kornahrens, Luiz Barbosa, Louise Walport, Matthew Tatton, Michael O'Hagan, Akshat Rathi, David Baker. J. Org. Chem., 2013, 78, 12338–12350. Selected as a Featured Article.
DOI: 10.1021/jo402388f
 


 

162. Modular Isoquinoline Synthesis Using Catalytic Enolate Arylation and In-Situ Functionalization
Ben Pilgrim, Alice Gatland, Charlie McTernan, Panayiotis Procopiou, Timothy Donohoe. Organic Letters, 2013, 15, 6190–6193.
DOI: 10.1021/ol4030309
 


 

161. Tethered Aminohydroxylation: Synthesis of the β-Amino Acid of Microsclerodermins A and B
Robert D. C. Pullin, Akshat H. Rathi, Ekaterina Y. Melikhova, Christian Winter, Amber L. Thompson and Timothy J. Donohoe. Org. Lett., 2013, 15, 5492–5495.
DOI: 10.1021/ol402638n
 


 

159. Vinyl Weinreb Amides: A Versatile Alternative to Vinyl Ketone Substrates for Heck Arylation
David B. Baker, Peter T. Gallagher and Timothy J. Donohoe. Tetrahedron, 2013, 69, 3690–3697.
DOI: 10.1016/j.tet.2013.03.009
 


 

158. Osmium-Catalyzed Oxidative Cyclization of Dienes and Their Derivatives
Ben S. Pilgrim and Timothy J. Donohoe. J. Org. Chem., 2013, 78, 2149–2167. Work from this paper featured in the cover picture for JOC.
DOI: 10.1021/jo302719y
 


 

157. Interplay of Cascade Oxidative Cyclisation and Hydride Shifts in the Synthesis of the ABC Spiroketal Ring System of Pectenotoxin-4
Timothy J. Donohoe and Radek Lipinski. Angew. Chem. Int. Ed., 2013, 52, 2491–2494. Designated as a Hot Article.
DOI: 10.1002/anie.201208919
 


 

156. Oxidative Cyclisation for the Synthesis of Complex THF-Containing Natural Products
Timothy J. Donohoe, Robert D. C. Pullin, Radoslaw M. Lipinski. Pure & Applied Chem., 2013, 85, 1175–1184.
DOI: 10.1351/PAC-CON-12-10-25
 


 

154. Asymmetric Synthesis of the Fully Elaborated Pyrrolidone Core of Oxazolomycin A
Timothy J. Donohoe, Timothy J. C. O'Riordan, Manuel Peifer, Christopher R. Jones, Timothy J. Miles. Organic Lett., 2012, 14, 5460–5463.
DOI: 10.1021/ol302541j
 


 

153. Natural Product Synthesis as a Challenging Test of Newly Developed Methodology
Timothy J. Donohoe, Robert D. C. Pullin. Chemical Commun., 2012, 48, 11924–11938.
DOI: 10.1039/C2CC36040C
 


 

152. Synthesis of Substituted Isoquinolines Utilizing Palladium-Catalyzed α-Arylation of Ketones
Timothy J. Donohoe, Ben S. Pilgrim, Geraint R. Jones and José A. Bassuto. Proc. Natl. Acad. Sci. US, 2012, 109, 11605–11608.
DOI: 10.1073/pnas.1206532109
 


 

151. A Green Approach to Fenton Chemistry: Hydroxylation of Salicylic Acid in Aqueous Medium Using Electrogeneration of Fenton's Reagent
Janjira Panchompoo, Leigh Aldous, Mikhail Kabeshov, Ben S. Pilgrim, Timothy J. Donohoe and Richard G. Compton. New. J. Chem., 2012, 36, 1265–1272.
DOI: 10.1039/C2NJ21007J
 


 

150. Hydrogen-Bonding-Mediated Directed Osmium Dihydroxylation
Timothy J. Donohoe, Carole J. R. Bataille, Paolo Innocenti. Organic Reactions, 2012, 76, 1–47.
DOI: 10.1002/0471264180.or076.01
 


 

149. Olefin Cross-Metathesis for the Synthesis of Heteroaromatic Compounds
Timothy J. Donohoe, John F. Bower and Louis K. M. Chan. Org. Biomol. Chem., 2012, 10, 1322–1328. Designated as a Hot Article.
DOI: 10.1039/C2OB06659A
 


 

148. Improvements in the Tethered Aminohydroxylation Reaction and Its Application to Total Synthesis
Timothy J. Donohoe, Cedric K. A. Callens, Adam R. Lacy, Christian Winter. Eur. J. Org. Chem., 2012, 4, 655–663. Plus cover picture for this issue.
DOI: 10.1002/ejoc.201101464
 


 

147. Direct Preparation of Thiazoles, Imidazoles, Imidazopyridines and Thiazolidines from Alkenes
Timothy J. Donohoe, Mikhail Kabeshov, Akshat Rathi and Ian E. D. Smith. Org. Biomol. Chem., 2012, 10, 1093–1101.
DOI: 10.1039/C1OB06587D
 


 

145. Amino Acid Based Reoxidants for Aminohydroxylation: Application to the Construction of Amino Acid-Aminoalcohol Conjugates
Timothy J. Donohoe, Cedric K. A. Callens, Aida Flores, Stefanie Mesch, Darren L. Poole and Ishmael A. Roslan. Angew. Chem. Int. Ed., 2011, 50, 10957–10960.
DOI: 10.1002/anie.201103293
 


 

144. Synthesis of 2,4,6-Trisubstituted Pyridines via an Olefin Cross-Metathesis/Heck-Cyclisation-Elimination Sequence
Timothy J. Donohoe, John F. Bower, David B. Baker, José A. Basutto, Louis K. M. Chan and Peter Gallagher. Chemical Commun., 2011, 47, 10611–10613.
DOI: 10.1039/C1CC14257G
 


 

143. Total Synthesis of (±)-Streptonigrin: De Novo Construction of a Pentasubstituted Pyridine Using Ring-Closing Metathesis
Timothy J. Donohoe, Christopher R. Jones and Luiz C. A. Barbosa. J. Am. Chem. Soc., 2011, 133, 16418–16421.
DOI: 10.1021/ja207835w
 


 

142. Surface Plasmon Resonance Imaging of Glycoarrays Identifies Novel and Unnatural Carbohydrate-Based Ligands for Potential Ricin Sensor Development
Margherita Fais, Rositsa Karamanska, Sarah Allman, Shirley A. Fairhurst, Paolo Innocenti, Antony J. Fairbanks, Timothy J. Donohoe, Benjamin G. Davis, David A. Russell and Robert A. Field. Chemical Science, 2011, 2, 1952–1959.
DOI: 10.1039/C1SC00120E
 


 

141. The Influence of Exocyclic Stereochemistry on the Tethered Aminohydroxylation Reaction
Timothy J. Donohoe, Adam R. Lacy, Akshat H. Rathi, and Daryl S. Walter. Chemistry: An Asian Journal, 2011, 6, 3214–3222.
DOI: 10.1002/asia.201100497
 


 

140. A Short and Efficient Synthesis of Neodysiherbaine A Using Catalytic Oxidative Cyclisation
Timothy J. Donohoe, Paul Winship, Matthew R. Tatton and Peter Szeto. Angew. Chem. Int. Ed., 2011, 50, 7604–7606.
DOI: 10.1002/anie.201102525
 


 

139. Dehydrogenation of Cyclic-Thioethers Bound to a [Rh(diphosphine)]+ Fragment
Romeao Dallanegra, Ben S. Pilgrim, Adrian B. Chaplin, Timothy J. Donohoe and Andrew S. Weller. Dalton Transactions, 2011, 40, 6626–6628.
DOI: 10.1039/C1DT10503E
 


 

138. Exerting Control over the Acyloin Reaction
Timothy J. Donohoe, Ali Jahanshahi, Michael J. Tucker, Farrah L. Bhatti, Ishmael A. Roslan, Mikhail Kabeshov and Gail Wrigley. Chemical Commun., 2011, 47, 5849–5851.
DOI: 10.1039/C1CC11654A
 


 

137. Intramolecular Hydride Addition to Pyridinium Salts: New Routes to Enantiopure Dihydropyridones
Timothy J. Donohoe, Matthew J. Connolly, Akshat H. Rathi and Lesley Walton. Organic Lett., 2011, 13, 2074–2077.
DOI: 10.1021/ol200478p
 


 

136. Palladium Nanoparticle-Modified Carbon Nanotubes for Electrochemical Hydrogenolysis in Ionic Liquids
Yao Meng, Leigh Aldous, Ben S. Pilgrim, Timothy J. Donohoe and Richard G. Compton. New Journal of Chemistry, 2011, 35, 1369–1375.
DOI: 10.1039/C1NJ20070D
 


 

135. Heteroaromatic Synthesis via Olefin Cross-Metathesis: Entry to Polysubstituted Pyridines
Timothy J. Donohoe, José Basutto, Akshat H. Rathi and John F. Bower. Organic Lett., 2011, 13, 1036–1039.
DOI: 10.1021/ol103088r
 


 

134. Recent Developments in Methodology for the Direct Oxyamination of Olefins
Timothy J. Donohoe, Aida Flores, Cedric K.A. Callens, Adam J. Lacy, Akshat H. Rathi. Chem. Eur. J., 2011, 17, 58–76.
DOI: 10.1002/chem.201002323
 


 

133. Osmium-Free Direct syn-Dihydroxylation of Alkenes
Carole J. R. Bataille and Timothy J. Donohoe. Chem. Soc. Rev., 2011, 40, 114–128.
DOI: 10.1039/B923880H