2015-2019
201. Stereoselective Synthesis of Alicyclic Ketones: A Hydrogen Borrowing Approach
Roly J. Armstrong, Wasim M. Akhtar, James R. Frost, Kirsten E. Christensen, Neil G. Stevenson, Timothy J. Donohoe. Tetrahedron, 2019, 75, 130680. Steve Davies honor issue, 1–9.
DOI: 10.1016/j.tet.2019.130680
200. Transition Metal Free Reductive Hydroxymethylation of Isoquinolines
Benjamin M. Reeves, Hamish B. Hepburn, Alex Grozavu, Peter J. Lindsay-Scott, Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2019, 58, 15697–15701.
DOI: 10.1002/anie.201908857
199. 1-(4-Methyl-2,6,7-trioxabicyclo[2.2.2]oct-1-yl)-ethane
Christopher Hall and Timothy J. Donohoe. Encyclopedia of Reagents for Organic Synthesis, 2019, ISBN 9780470842898
198. Photochemical Alkene Isomerisation for the Synthesis of Polysubstituted Furans and Pyrroles Under Neutral Conditions
Johannes C. L. Walker, Simon Werrel and Timothy J. Donohoe. Chemistry: A European Journal, 2019, 5, 13114–13118.
DOI: 10.1002/chem.201903590
197. Hypervalent Iodine Initiated Intramolecular Alkene Dimerization: A Stereodivergent Entry to Cyclobutanes
Yuxiang Zhu, Ignacio Colomer and Timothy J. Donohoe. Chemical Communications, 2019, 55, 10316–10319.
DOI: 10.1039/C9CC04383G
196. Catalytic Asymmetric Synthesis of Cyclohexanes by Hydrogen Borrowing Annulations
Roly J. Armstrong, Wasim M. Akhtar, Tom A. Young, Fernanda Duarte and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2019, 58, 12558–12562.
DOI: 10.1002/anie.201907514
195. Rhodium-Catalysed Vinyl 1,4-Conjugate Addition Coupled with Sharpless Asymmetric Dihydroxylation in the Synthesis of the CDE Ring Fragment of Pectenotoxin 4
Melodie Richardson, Darren Poole, Christopher Tame, Timothy J. Donohoe. Chem. Sci., 2019, 10, 6336–6340.
DOI: 10.1039/C9SC01761E
194. HFIP Solvent Enables Alcohols to Act as Alkylating Agents in Stereoselective Heterocyclisation
Yuxiang Zhu, Ignacio Colomer, Timothy J. Donohoe. J. Am. Chem. Soc., 2019, 141, 6489–6493.
DOI: 10.1021/jacs.9b02198
193. Synthesis of Lamellarin Alkaloids Using Orthoester-Masked α-Keto Acids
Harry J. Shirley, Maria Koyioni, Filip Muncan, Timothy J. Donohoe. Chem. Sci., 2019, 10, 4334–4338.
DOI: 10.1039/C8SC05678A
192. The Reductive C3 Functionalization of Pyridinium and Quinolinium Salts Through Iridium-Catalysed Interrupted Transfer Hydrogenation
Alexandru Grozavu, Hamish B. Hepburn, Philip J. Smith, Harish K. Potukuchi, Peter J. Lindsay-Scott, Timothy J. Donohoe. Nature Chemistry, 2019, 11, 242–247.
DOI: 10.1038/s41557-018-0178-5
191. Stereoselective Synthesis of Cyclohexanes via an Iridium Catalysed (5+1) Annulation Strategy
Wasim M. Akhtar, Roly J. Armstrong, James R. Frost, N. G. Stevenson, Timothy J. Donohoe. J. Am. Chem. Soc., 2018, 140, 11916–11920.
DOI: 10.1021/jacs.8b07776
190. OBO-Protected Pyruvates as Reagents for the Synthesis of Functionalized Heteroaromatic Compounds
C. Henrique Alves Estavez, Maria Koyioni, Kirsten E. Christensen, Peter D. Smith, Timothy J. Donohoe. Organic Letters, 2018, 20, 4048–4051.
DOI: 10.1021/acs.orglett.8b01614
189. Asymmetric Total Synthesis of (−)-(3R)-Inthomycin C
Sandra Balcells, Maxwell B. Haughey, Johannes C. L. Walker, Laia Josa-Cullere, Christopher Towers, Timothy J. Donohoe. Organic Letters, 2018, 20, 3583–3586.
DOI: 10.1021/acs.orglett.8b01370
188. The Efficacy of the Quercetin Analogue LY294002 in Immortalized Cancer Cell Lines Is Related to the Oxygenic and Metabolic Status of Cells
Xinyue Huang, Michelle Potter, Ben Pilgrim, Ruchuta Ardkhean, Mikail Kabeshov, Timothy Claridge, Matthew Wiseman, Karl Jonathan Morten, Timothy Donohoe, Helen Elizabeth Townley. Int. J. Cancer Ther. Oncol., 2017, 5, 51X.
DOI: 10.14319/ijcto.51.14
187. Cobalt versus Osmium: Control of Both Trans and Cis Selectivity in Construction of the EFG Rings of Pectenotoxin 4
Ahria Roushanbakhti, Yifan Liu, Paul C. M. Winship, Michael J. Tucker, Wasim M. Akhtar, Daryl S. Walter, Gail Wrigley and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2017, 56, 14883–14887.
DOI: 10.1002/anie.201708278
186. Hexafluoroisopropanol as a Highly Versatile Solvent
Ignacio Colomer, Anna E. R. Chamberlain, Maxwell B. Haughey and Timothy J. Donohoe. Nature Reviews Chemistry, 2017, 1, 0088.
DOI: 10.1038/s41570-017-0088
185. Pyruvate Enolate Arylation and Alkylation: OBO Ester Protected Pyruvates as Useful Reagents in Organic Synthesis
Carlos Henrique Esteves, Christopher J. J. Hall, Peter Smith and Timothy J. Donohoe. Organic Letters, 2017, 19, 5248–5251.
DOI: 10.1021/acs.orglett.7b02524
184. Catalytic Enolate Arylation with 3-Bromoindoles Allows the Formation of Beta-Carbolines
C. Henrique Estavez Alves, Peter D. Smith, and Timothy J. Donohoe. J. Org. Chem., 2017, 82, 4435–4443.
DOI: 10.1021/acs.joc.7b00299
183. Hydrogen Borrowing Catalysis with Secondary Alcohols: A New Route for the Generation of β-Branched Carbonyl Compounds
Wasim M. Akhtar, Choon Boon Cheong, James R. Frost, Kirsten E. Christensen, Neil G. Stevenson, and Timothy J. Donohoe. J. Am. Chem. Soc., 2017, 139, 2577–2580.
DOI: 10.1021/jacs.6b12840
182. Diastereoselective Synthesis of the 5-Hydroxy-Pyrrolidinone Amino Acid of the Microsclerodermins and Model Studies for an End-Game Strategy for Microsclerodermin B
Christian Winter, Robert D. C. Pullin and Timothy J. Donohoe. Tetrahedron Letters, 2017, 58, 602–605.
DOI: 10.1016/j.tetlet.2016.12.045
181. Orthogonally Protected 1,2 Diols from Electron-Rich Alkenes Using Metal Free Olefin Syn Dihydroxylation
Ignacio Colomer, Rosimeire Coura Barcelos, Kirsten E. Christensen, Timothy J. Donohoe. Organic Letters, 2016, 18, 5880–5883.
DOI: 10.1021/acs.orglett.6b02959
180. Dehydromicrosclerodermin B and Microsclerodermin J: Total Synthesis and Structural Revision
Ekaterina Y. Melikhova, Robert D. C. Pullin, Christian Winter, Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2016, 55, 9753–9757.
DOI: 10.1002/ange.201604764
179. Hydrogen Bonding to Hexafluoroisopropanol Controls the Oxidative Strength of Hypervalent Iodine Reagents
Ignacio Colomer, Christopher Batchelor-McAuley, Barbara Odell, Timothy J. Donohoe, Richard Compton. J. Am. Chem. Soc., 2016, 138, 8855–886.
DOI: 10.1021/jacs.6b04057
178. Iridium-Catalyzed C4-Alkylation of 2,6-Di-tert-butylphenol Using Hydrogen Borrowing Catalysis
James R. Frost, Choon Boon Cheong, Timothy J. Donohoe. Synthesis, 2016, 49, 910–916.
DOI: 10.1055/s-0035-1561439
177. Synthesis of Aromatic Heterocycles Using Ring-Closing Metathesis
Harish K. Potukuchi, Ignacio Colomer, Timothy J. Donohoe. Advances in Heterocyclic Chemistry: Alan Katritzky Tribute Volume, Chapter 15, 2016, Elsevier, 43–65.
DOI: 10.1016/bs.aihch.2016.04.006
176. Catalytic Hypervalent Iodine Promoters Allow Styrene Dimerisation and the Formation of Tri- and Tetrasubstituted Cyclobutanes
Ignacio Colomer, Rosimeire Coura Barcelos and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2016, 55, 4748–4752.
DOI: 10.1002/anie.201511683
175. Palladium-Catalysed Enolate Arylation as a Key C-C Bond Forming Reaction for the Synthesis of Isoquinolines
Ben S. Pilgrim, Alice E. Gatland, Carlos H. A. Estaves, Charlie T. McTernan, Geraint R. Jones, Matthew R. Tatton, Panayiotis A. Procopiou, Timothy J. Donohoe. Organic and Biomolecular Chemistry, 2016, 14, 1065–1090. Designated as a HOT article.
DOI: 10.1039/C5OB02320C
174. Strategic Application and Transformation of Ortho-Di-Substituted Phenyl and Cyclopropyl Ketones to Expand the Scope of Hydrogen Borrowing Catalysis
James R. Frost, Choon Boon Cheong, Wasim M. Akhtar, Dimitri F. J. Caputo, Neil G. Stevenson and Timothy J. Donohoe. J. Am. Chem. Soc., 2016, 137, 15664–15667.
DOI: 10.1021/jacs.5b11196
173. Application of Catalytic Z-Selective Olefin Metathesis in Natural Product Synthesis
Simon Werrel, Johannes C. L. Walker and Timothy J. Donohoe. Tetrahedron Letters, 2015, 56, 5261–5268.
DOI: 10.1016/j.tetlet.2015.07.008
172. Aziridine Electrophiles in the Functionalisation of Peptide Chains with Amine Nucleophiles
Anatol P. Spork and Timothy J. Donohoe. Organic and Biomolecular Chemistry, 2015, 13, 8545–8549.
DOI: 10.1039/C5OB00856E
171. Modular Synthesis of Highly Substituted Pyridines via Enolate α-Alkenylation
Leo A. Hardegger, Jacqueline Habegger and Timothy J. Donohoe. Organic Letters, 2015, 17, 3222–3225.
DOI: 10.1021/acs.orglett.5b01312
170. Palladium-Catalyzed Alpha-Arylation of Carbonyls in the De Novo Synthesis of Aromatic Heterocycles
Harish K. Potukuchi, Anatol P. Spork and Timothy J. Donohoe. Organic and Biomolecular Chemistry, 2015, 13, 4367–4373.
DOI: 10.1039/C5OB00055F
169. Hydrogen Borrowing and Interrupted Hydrogen Borrowing Reactions of Ketones and Methanol, Catalysed by Iridium
Di Shen, Darren L. Poole, Camilla C. Shotton, Anne F. Kornahrens, Mark P. Healy and Timothy J. Donohoe. Angewandte Chemie Int. Ed., 2015, 54, 1642–1645.
DOI: 10.1002/anie.201410391